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Furthermore, when rates of nausea and vomiting were examined in 298 patients that had estrogen measured in the 10 days prior to GLP1R agonist initiation, we found that higher serum estradiol levels were clearly predictive of increased rates of nausea and vomiting in this cohort (Fig 5F)

doi: 10.1126/science.1059042 47 FukamiK.YoshidaM.InoueT.KurokawaM.FissoreR

These effects were in line with expectations, Drucker says

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Any changes to your vision should be reported promptly to your ophthalmologist